Clarapath was founded as a spin-off of Partha Mitra's research on high throughput neuroanatomy, using the tape-transfer method for facilitating high quality microtomy (cutting tissue into micrometer thin sections for further analysis).
The tape transfer method was originally developed to facilitate the transport of micrometer-thin frozen tissue sections to glass slides for clinical application of anatomic pathology. Dr Mitra adopted the technique to permit acquisition of distortion-free microtome cut frozen sections to facilitate whole-brain digital neuroanatomy research.
Clarapath has taken the method back to the clinical space and the anatomic pathology laboratory, by transferring the methodology to paraffin-cut sections and by developing a fully automated system that takes tissue blocks as inputs and provides glass slides with tissue on them as output. This will provide the final missing link to end-to-end automation of the anatomic pathology laboratory.
Originally launched as pTerapipe in 2011, Clarapath commenced operations in July 2014 at the New York Genome Center. In 2016 it formed a close partnership with the Northwell Health Systems with the goal of using the technology to transformatively improve patient care in anatomic pathology.